May 26, 2009 (CIDRAP News) –Two vaccine companies, Sanofi Pasteur and GlaxoSmithKline, recently announced they received their first orders from the US government for a vaccine and adjuvant to protect the country against the novel H1N1 virus.Sanofi, in a statement released yesterday, said the initial order it received from the Department of Health and Human Services (HHS) covers the production of bulk vaccine and related activities and is worth $190 million. On May 22, Glaxo said in a press release that HHS ordered vaccine antigen and the company’s proprietary adjuvant system, AS03. Adjuvants are compounds that enhance a vaccine’s immune response, offering the possibility of stretching antigen supplies.The announcements from the two companies follow a May 22 announcement from HHS that secretary Kathleen Sebelius was directing about $1 billion in existing funds toward clinical studies and commercial production of bulk vaccine antigen and adjuvant.Federal officials have announced plans to support the development of a novel H1N1 vaccine, but have taken pains to explain that the decision to use it would be made separately.The Centers for Disease Control and Prevention (CDC) has said it hopes to wrap up work on a seed strain to send to vaccine makers within the next few weeks. Once companies receive the seed strain, they can develop pilot lots to begin safety, efficacy, and dosage testing.The federal government’s placement of the orders falls under existing contracts that the Biomedical Advanced Research and Development Authority (BARDA) established with the companies in 2004 as part of the nation’s pandemic influenza strategy.Sanofi said it hopes to begin work on a pilot lot in June after the US Food and Drug Administration approves its working seed. The company said clinical trials could begin as early as August, but a timeline for final formulation, filling, and distribution has not been set.Wayne Pisano, Sanofi’s president and chief executive officer, said in the press release that though a number of complex steps need to be taken before a vaccine is available, the company’s experience in developing the prepandemic H5N1 avian influenza vaccine will be helpful. “We look forward to further demonstrating our experience and expertise in vaccine development as we prepare for this new threat from AH1N1,” he said.Production of the new H1N1vaccine for HHS will take place at the company’s recently licensed new production facility in Swiftwater, Pa. As soon as the company finishes production of seasonal influenza vaccine at its second Swiftwater facility, it can produce the novel H1N1 vaccine at both plants. The two plants, when operating at full capacity, can make about 150 million doses of seasonal flu vaccine.Meanwhile, Glaxo said it expects to fill HHS’ adjuvant order within the next few months and hopes to produce the first antigen doses 4 to 6 months after receiving the novel H1N1seed strain. The company said its proprietary adjuvant, already approved as a component of the H5N1 vaccine in Europe and some Asian countries, is the subject of 15 additional clinical trials, including one involving a seasonal flu vaccine.Both Sanofi and Glaxo said they are in ongoing discussions with other countries about producing novel flu vaccine for national stockpiles.See also:May 25 Sanofipress releaseMay 22 Glaxopress releaseMay 22 HHS press releaseMay 6 CIDRAP News story “FDA approves new vaccine facility”
RelatedPosts Aruna Quadri’s uncommon qualities stand him out, says Oshodi Quadri Aruna leads Africa to World Cup Aruna’s arrival attracted interest in Germany — TTBL Nigeria’s Aruna Quadri has teamed with a top club in the German Bundesliga Table Tennis league after the world number 18 was unveiled on Monday by the management of the club led by its President, Stefan Frauenholz. The deal was brokered by WEOAllSports and Quadri is expected to join the club – TTC RhönSprudel Maberzell Fulda – based in the Central part of Germany, from next season (September 2020) in the elite division of the Bundesliga. According to Frauenholz, the decision to sign Quadri was based on the team’s conviction that the Nigerian has a lot to offer based on his global exploits. “We are so lucky to sign Aruna Quadri because he is such a good player with excellent results. This is a family club and we believe his passion and interest tally with the ideals of the club. We are so happy to unveil him today and we hope he can bring his wealth of experience to help the team next season,” Frauenholz said. An excited Quadri said he was happy fulfilling his dream of playing in the German Bundesliga having spent over 10 years playing in the Portuguese league with several laurels to show for his efforts. “I am happy joining this team and I see that it is a family club with good ideal and for me I am going to give my 100 percent to the team. I look forward to having a good experience playing against the best in the Bundesliga to continue to improve my career,” the Rio 2016 Olympic quarterfinalist said. For the Chairman of WEOAllSports, Wahid Oshodi, the signing of Quadri by the German club is a confirmation of his hardwork and commitment to his trade. Oshodi said: “We are so excited that teams across Europe appreciate the progress Quadri has made over the years. He is now one of the best players in the world and we hope this move will give him the opportunity to improve his skills and continue to improve his global rating. The Bundesliga has the best players in the world and Quadri will feel at home there. Aruna Quadri is such an amazing player who is very popular among the Germans and we are not surprised that some of the best teams in the world wanted him. We hope this will serve as an inspiration for the younger Nigerian players.” Quadri started his sojourn to Europe in 2010 and he has played for several clubs in Portugal, while his present team is Sporting, where he had won several medals, including making it to the semifinal stage of the ETTU Champions League. At Sporting, he has remained unbeaten in the last five years, while he has won back-to-back league titles with the Lisbon-based team.Tags: aruna quadriGerman Bundesliga Table Tennis LeagueWEOAllsports
With the international tournament fast approaching, here’s a breakdown of Team Canada’s roster and its FIBA World Cup schedule.FIBA WORLD CUP 2019: Team USA roster, game scheduleTeam Canada roster for 2019 FIBA World CupPlayerPositionCurrent TeamKhem BirchCenterOrlando MagicChris BoucherCenterToronto RaptorsOshae BrissettForwardSyracuse Orange (NCAA)Aaron DoornekampForwardValencia Basket (Spain)Luguentz DortGuardOklahoma City ThunderMelvin EjimForwardBC UNICS (Russia)Brady HeslipGuardIstanbul BBSK (Turkey)Cory JosephGuardSacramento KingsNaz Mitrou-LongGuardSalt Lake City Stars (G League)Andrew NembhardGuardFlorida Gators (NCAA)Kelly OlynykForwardMiami HeatKevin PangosGuardFC Barcelona (Spain)Phil ScrubbGuardZenit Saint Petersburg (Russia)Thomas ScrubbForwardOpenjobmetis Varese (Italy)Marial ShayokForwardPhiladelphia 76ersAndy RautinsGuardBahcesehir Koleji Istanbul (Turkey)Kyle WiltjerForwardUnicaja Malaga (Spain)Players not participating: Nickeil Alexander-Walker (New Orleans Pelicans), RJ Barrett (New York Knicks), Dillon Brooks (Memphis Grizzlies), Brandon Clarke (Memphis Grizzlies), Shai Gilgeous-Alexander (Oklahoma City Thunder), Mfiondu Kabengele (Los Angeles Clippers), Trey Lyles (San Antonio Spurs), Jamal Murray (Denver Nuggets), Dwight Powell (Dallas Mavericks), Nik Stauskas (Baskonia — Spain), Tristan Thompson (Cleveland Cavaliers), Andrew Wiggins (Minnesota Timberwolves)Team Canada exhibition scheduleMatchupDateTimeCanada vs. NigeriaAug. 77 p.m. ETCanada vs. NigeriaAug. 98 p.m. ETCanada vs. AustraliaAug. 165:30 a.m. ETCanada vs. AustraliaAug. 175:30 a.m. ETCanada vs. New ZealandAug. 205:30 a.m. ETCanada vs. New ZealandAug. 215:30 a.m. ETCanada vs. USAAug. 265:30 a.m. ETTeam Canada schedule for 2019 FIBA World CupMatchupDateTimeCanada vs. AustraliaSept. 13:30 a.m. ETCanada vs. LithuaniaSept. 37:30 a.m. ETCanada vs. SenegalSept. 53:30 a.m. ETSecond roundSept. 6-9TBDQuarterfinalsSept. 10-11TBDSemifinalsSept. 13TBDFinalsSept. 15TBD Which players will fill out the roster for Team Canada ahead of the 2019 FIBA World Cup?Nearly 30 Canadians were invited to training camp and, similar to Team USA, there have already been several dropouts. Head coach Nick Nurse will need to squeeze as much as he can out of the available players in order to compete in a tough Group H against Australia, Lithuania and Senegal. But he won’t be afraid of a challenge after winning the 2019 NBA championship with the Raptors.
Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award Kiss-and-tell matinee idol’s conquests: True stories or tall tales? Jo Koy: My brain always wants to think funny Coco’s house rules on ‘Probinsyano’ set CEU’s Ebondo to backstop Congo in African qualifiers It’s too early to present Duterte’s ‘legacy’ – Lacson But fate works in mysterious ways and Pogoy found himself back with a familiar face in Nash Racela, who is now calling the shots for TNT.Fast forward to today, and the 6-foot-2 swingman is still in disbelief with what he has achieved in his first year in the pros as he won the Rookie of the Year honors this season.FEATURED STORIESSPORTSRedemption is sweet for Ginebra, Scottie ThompsonSPORTSMayweather beats Pacquiao, Canelo for ‘Fighter of the Decade’SPORTSFederer blasts lack of communication on Australian Open smog“It’s indescribable. I feel nervous and I don’t know what to feel. I really can’t put to words what I feel right now. In my mind, it’s all a dream,” he said after receiving his trophy in the 2017 Leo Awards on Friday.Pogoy seamlessly blended in with the KaTropa’s rotation, with Racela immediately thrusting him to the starting small forward spot. View comments Don’t miss out on the latest news and information. MOST READ Sports Related Videospowered by AdSparcRead Next Jake says relationship with Shaina ‘goes beyond physical attraction’ There, the 25-year-old thrived as he learned from premier playmaker Jayson Castro and the rest of the veteran TNT core en route to them leading the squad to three semifinals appearances this season and a runner-up finish in the 2017 Commissioner’s Cup.Wrapping up his a successful first year in the pros, Pogoy thinks the award is a testament of the effort he put in under Racela.“This is the result of my hardwork because every practice, I always do extra work,” he said.But Pogoy remains unsatisfied as he hopes to receive a trophy the whole team could be proud of.“I know I still have lots to work on. This Rookie of the Year award is just a bonus. What’s important is to be a champion and that’s really my goal,” he said.ADVERTISEMENT OSG plea to revoke ABS-CBN franchise ‘a duplicitous move’ – Lacson Margot Robbie talks about filming ‘Bombshell’s’ disturbing sexual harassment scene Jake says relationship with Shaina ‘goes beyond physical attraction’ LATEST STORIES Coco’s house rules on ‘Probinsyano’ set Photo by Tristan Tamayo/ INQUIRER.netFrom the very beginning, Roger Pogoy never expected that he would make a big impact compared to his contemporaries in Far Eastern University.Playing third fiddle to the likes of Mac Belo and Mike Tolomia, the Cebuano shooter has always just been regarded as a valuable role player.ADVERTISEMENT